Reactions 1364 - 13 Aug 2011

Antineoplastics

Oral mucositis in a child: case reportA 5-year-old girl with acute lymphoblastic leukaemia

developed oral mucositis while receiving chemotherapywith antineoplastics [dosages and some routes not stated].

The girl commenced treatment with daunorubicin,asparaginase, prednisone and vincristine, as well asintrathecal cytarabine, dexamethasone and methotrexate.On the fifth day of chemotherapy, after administration ofthe second dose of daunorubicin, she presented withfebrile neutropenia. She had also developed cellulitis of herleft ring finger and oral mucositis, with multiple ulcers onher lips, labial commissure and tongue, as well as tongueerythema and lip oedema. Test results were consistent withan infection.

The girl received meropenem and vancomycin, afterwhich her neutropenia resolved. She also receivedchlorhexidine for oral hygiene and underwent daily light-emitting diode therapy to treat her mucositis and cellulitislesions. On the tenth day of treatment, her lesions hadresolved.Rimulo AL, et al. Chemotherapy-induced oral mucositis in a patient with acutelymphoblastic leukaemia. European Archives of Paediatric Dentistry 12: 124-7,No. 2, Apr 2011 - Brazil 803058839

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Reactions 13 Aug 2011 No. 13640114-9954/10/1364-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved