Antineoplastics
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Reactions 1364 - 13 Aug 2011 Antineoplastics Oral mucositis in a child: case report A 5-year-old girl with acute lymphoblastic leukaemia developed oral mucositis while receiving chemotherapy with antineoplastics [dosages and some routes not stated]. The girl commenced treatment with daunorubicin, asparaginase, prednisone and vincristine, as well as intrathecal cytarabine, dexamethasone and methotrexate. On the fifth day of chemotherapy, after administration of the second dose of daunorubicin, she presented with febrile neutropenia. She had also developed cellulitis of her left ring finger and oral mucositis, with multiple ulcers on her lips, labial commissure and tongue, as well as tongue erythema and lip oedema. Test results were consistent with an infection. The girl received meropenem and vancomycin, after which her neutropenia resolved. She also received chlorhexidine for oral hygiene and underwent daily light- emitting diode therapy to treat her mucositis and cellulitis lesions. On the tenth day of treatment, her lesions had resolved. Rimulo AL, et al. Chemotherapy-induced oral mucositis in a patient with acute lymphoblastic leukaemia. European Archives of Paediatric Dentistry 12: 124-7, No. 2, Apr 2011 - Brazil 803058839 1 Reactions 13 Aug 2011 No. 1364 0114-9954/10/1364-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved
Transcript of Antineoplastics
Reactions 1364 - 13 Aug 2011
Antineoplastics
Oral mucositis in a child: case reportA 5-year-old girl with acute lymphoblastic leukaemia
developed oral mucositis while receiving chemotherapywith antineoplastics [dosages and some routes not stated].
The girl commenced treatment with daunorubicin,asparaginase, prednisone and vincristine, as well asintrathecal cytarabine, dexamethasone and methotrexate.On the fifth day of chemotherapy, after administration ofthe second dose of daunorubicin, she presented withfebrile neutropenia. She had also developed cellulitis of herleft ring finger and oral mucositis, with multiple ulcers onher lips, labial commissure and tongue, as well as tongueerythema and lip oedema. Test results were consistent withan infection.
The girl received meropenem and vancomycin, afterwhich her neutropenia resolved. She also receivedchlorhexidine for oral hygiene and underwent daily light-emitting diode therapy to treat her mucositis and cellulitislesions. On the tenth day of treatment, her lesions hadresolved.Rimulo AL, et al. Chemotherapy-induced oral mucositis in a patient with acutelymphoblastic leukaemia. European Archives of Paediatric Dentistry 12: 124-7,No. 2, Apr 2011 - Brazil 803058839
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Reactions 13 Aug 2011 No. 13640114-9954/10/1364-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved
