Antineoplastics
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Reactions 1289 - 20 Feb 2010 S Antineoplastics Pseudoaneurysm in an elderly patient: case report A 75-year-old man developed a renal artery pseudoaneurysm during chemotherapy with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone or prednisolone * (R-CHOP) The man presented with left flank pain and weight loss. Abdominal lymph node swelling and a renal mass occupying the whole left kidney were observed. He underwent needle biopsy of the left kidney, and was diagnosed with diffuse large B-cell lymphoma. He began receiving R-CHOP [dosages not stated]. During chemotherapy, he experienced intermittent left flank pain, and his haemoglobin level gradually decreased. After three cycles of R-CHOP, enhanced CT scan revealed intratumoural haemorrhage and saccular pseudoaneurysm in the left renal artery. After the fifth cycle, his tumour began to enlarge, and he became transfusion dependent for severe anaemia. Repeat contrast CT scan revealed expansion of the pseudoaneurysm and intratumoural haemorrhage. The man underwent coil embolisation with successful occlusion of the pseudoaneurysm. Thereafter, his tumour gradually shrank, and he became transfusion independent. Author comment: "We report here a case of non- traumatic [renal artery pseudoaneurysm] due to chemotherapy for diffuse large B-cell lymphoma". * It was not specified whether this patient was receiving prednisone or prednisolone Masamoto Y, et al. A case report of non-traumatic renal artery pseudoaneurysm due to chemotherapy for diffuse large B-cell lymphoma. Annals of Hematology 89: 107-108, No. 1, Jan 2010. Available from: URL: http://dx.doi.org/10.1007/ s00277-009-0776-9 - Japan 803006284 1 Reactions 20 Feb 2010 No. 1289 0114-9954/10/1289-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved
Transcript of Antineoplastics
Reactions 1289 - 20 Feb 2010
SAntineoplastics
Pseudoaneurysm in an elderly patient: casereport
A 75-year-old man developed a renal arterypseudoaneurysm during chemotherapy with rituximab,cyclophosphamide, doxorubicin, vincristine andprednisone or prednisolone* (R-CHOP)
The man presented with left flank pain and weight loss.Abdominal lymph node swelling and a renal massoccupying the whole left kidney were observed. Heunderwent needle biopsy of the left kidney, and wasdiagnosed with diffuse large B-cell lymphoma. He beganreceiving R-CHOP [dosages not stated]. Duringchemotherapy, he experienced intermittent left flank pain,and his haemoglobin level gradually decreased. Afterthree cycles of R-CHOP, enhanced CT scan revealedintratumoural haemorrhage and saccular pseudoaneurysmin the left renal artery. After the fifth cycle, his tumourbegan to enlarge, and he became transfusion dependent forsevere anaemia. Repeat contrast CT scan revealedexpansion of the pseudoaneurysm and intratumouralhaemorrhage.
The man underwent coil embolisation with successfulocclusion of the pseudoaneurysm. Thereafter, his tumourgradually shrank, and he became transfusion independent.
Author comment: "We report here a case of non-traumatic [renal artery pseudoaneurysm] due tochemotherapy for diffuse large B-cell lymphoma".
* It was not specified whether this patient was receivingprednisone or prednisolone
Masamoto Y, et al. A case report of non-traumatic renal artery pseudoaneurysmdue to chemotherapy for diffuse large B-cell lymphoma. Annals of Hematology 89:107-108, No. 1, Jan 2010. Available from: URL: http://dx.doi.org/10.1007/s00277-009-0776-9 - Japan 803006284
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Reactions 20 Feb 2010 No. 12890114-9954/10/1289-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved
