Reactions 1415 - 18 Aug 2012

SAntineoplastics

Febrile neutropenia and bacterial pneumonia inan elderly patient: case report

A man developed febrile neutropenia and bacterialpneumonia while receiving antineoplastic therapy forrecurrent thymic carcinoma. Following a diagnosis ofthymic carcinoma in July 2002, the man received five cyclesof cisplatin, doxorubicin, vincristine andcyclophosphamide (ADOC), with a good response. TheADOC regimen [dosages and routes not stated] wasrestarted in August 2011 due to a recurrence of thymiccancer, but he developed febrile neutropenia and bacterialpneumonia during the first cycle. He refused furtherantineoplastic therapy and remained under observationwithout symptoms [outcome not clearly stated].

Author comment: "One patient developed neutropenicfever and pneumonia during the first cycle of ADOCreadministration, resulting in a deteriorated performancestatus (PS) of 2."Nomura Y, et al. Successful retreatment with ADOC chemotherapy in relapsedthymic carcinoma: Experiences in two cases. World Journal of Oncology 3: 33-36,No. 1, Feb 2012. Available from: URL: http://dx.doi.org/10.4021/wjon435w -Japan 803075365

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Reactions 18 Aug 2012 No. 14150114-9954/10/1415-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved