Antineoplastics
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Reactions 1493, p9 - 22 Mar 2014 S Antineoplastics Cough, fever, neutropenia and thrombocytopenia: case report A 58-year-old man, with an 8-year, long-term survival of limited-stage small cell lung cancer, was diagnosed with diffuse large B cell lymphoma of the left supraclavicular lymph node. He received radiation of the left neck and chemotherapy with CHOP-R for four cycles and then CEPP-R for two cycles [dosages and routes not stated]. * He was subsequently admitted to an emergency room for intractable cough, low- grade fever, severe neutropenia and thrombocytopenia due to intense chemotherapy [time to reaction onset not clearly stated]. He received antibacterials; in addition, he underwent a platelet transfusion due to underlying cirrhosis and variceal bleeding. On last follow-up he was in complete remission [patient outcome not clearly stated]. Author comment: "He was admitted . . . for intractable cough, low grade fever, severe neutropenia and thrombocytopenia secondary to intense chemotherapy treatment." * Details of regimens not stated. CHOP-R usually comprises cyclophosphamide, doxorubicin, vincristine, prednisone or prednisolone, and rituximab; CEPP-R usually comprises cyclophosphamide, etoposide, prednisone or prednisolone, procarbazine and rituximab. Feng D, et al. A long-term survival of small cell lung cancer developed diffuse large B-Cell lymphoma. Internet Journal of Pulmonary Medicine 14: No. 1, Jan 2013 - USA 803100664 1 Reactions 22 Mar 2014 No. 1493 0114-9954/14/1493-0001/$14.95 Adis © 2014 Springer International Publishing AG. All rights reserved
Transcript of Antineoplastics
Reactions 1493, p9 - 22 Mar 2014
SAntineoplastics
Cough, fever, neutropenia and thrombocytopenia:case report
A 58-year-old man, with an 8-year, long-term survival oflimited-stage small cell lung cancer, was diagnosed withdiffuse large B cell lymphoma of the left supraclavicular lymphnode. He received radiation of the left neck and chemotherapywith CHOP-R for four cycles and then CEPP-R for two cycles[dosages and routes not stated].* He was subsequentlyadmitted to an emergency room for intractable cough, low-grade fever, severe neutropenia and thrombocytopenia due tointense chemotherapy [time to reaction onset not clearlystated]. He received antibacterials; in addition, he underwent aplatelet transfusion due to underlying cirrhosis and varicealbleeding. On last follow-up he was in complete remission[patient outcome not clearly stated].
Author comment: "He was admitted . . . for intractablecough, low grade fever, severe neutropenia andthrombocytopenia secondary to intense chemotherapytreatment."
* Details of regimens not stated. CHOP-R usually comprisescyclophosphamide, doxorubicin, vincristine, prednisone orprednisolone, and rituximab; CEPP-R usually comprisescyclophosphamide, etoposide, prednisone or prednisolone,procarbazine and rituximab.
Feng D, et al. A long-term survival of small cell lung cancer developed diffuselarge B-Cell lymphoma. Internet Journal of Pulmonary Medicine 14: No. 1, Jan2013 - USA 803100664
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Reactions 22 Mar 2014 No. 14930114-9954/14/1493-0001/$14.95 Adis © 2014 Springer International Publishing AG. All rights reserved
