Lorazepam overdose
1
Reactions 1379 - 26 Nov 2011 O S Lorazepam overdose Unresponsiveness in an elderly patient, treated with flumazenil: case report A 70-year-old man became unresponsive after starting an iatrogenic overdose of IV lorazepam. He was treated with flumazenil. The man had been hospitalised for more than 180 days with a complicated course. His prescription was intended to be IV lorazepam 1mg every 4 hours as required for nausea or emesis. However, due to multiple errors, the man began receiving 60mg every 4 hours, and became unresponsive [duration of treatment to reaction onset not stated]. The man received a flumazenil drip at 1.0mg/hour for more than 48 hours [outcome not stated]. Wiegand T, et al. High-dose flumazenil drip for reversal of a massive iatrogenic benzodiazepine overdose A cause-effect analysis of an Adverse Drug Effect and discussion of the role of the Clinical Pharmacist and Medical Toxicologist. 2011 North American Congress of Clinical Toxicology : abstr. 113, 21 Sep 2011. Available from: URL: http://www.clintox.org/meetings.cfm - USA 803063277 1 Reactions 26 Nov 2011 No. 1379 0114-9954/10/1379-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved
Transcript of Lorazepam overdose
Reactions 1379 - 26 Nov 2011
O SLorazepam overdose
Unresponsiveness in an elderly patient, treatedwith flumazenil: case report
A 70-year-old man became unresponsive after starting aniatrogenic overdose of IV lorazepam. He was treated withflumazenil.
The man had been hospitalised for more than 180 dayswith a complicated course. His prescription was intendedto be IV lorazepam 1mg every 4 hours as required fornausea or emesis. However, due to multiple errors, theman began receiving 60mg every 4 hours, and becameunresponsive [duration of treatment to reaction onset notstated].
The man received a flumazenil drip at 1.0mg/hour formore than 48 hours [outcome not stated].Wiegand T, et al. High-dose flumazenil drip for reversal of a massive iatrogenicbenzodiazepine overdose A cause-effect analysis of an Adverse Drug Effect anddiscussion of the role of the Clinical Pharmacist and Medical Toxicologist. 2011North American Congress of Clinical Toxicology : abstr. 113, 21 Sep 2011.Available from: URL: http://www.clintox.org/meetings.cfm - USA 803063277
1
Reactions 26 Nov 2011 No. 13790114-9954/10/1379-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved
