Antineoplastics
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Reactions 430 - 5 Dec 1992 Antineoplastics Bacillary angiomatosis in a child: case report An erythematous nodule appeared above the left eyebrow of a 12-year-old boy 11 months after he was diagnosed with leukaemia. The patient had received prednisone, vincristine, asparaginase, mercaptopurine, methotrexate, cytarabine and hydrocortisone as remission induction and maintenance therapy. Consolidation therapy consisted of 6 courses of methotrexate and asparaginase. Antibiotic therapy reduced the size of the nodule but the lesion persisted. A diagnosis of bacillary angiomatosis was confirmed by results of a biopsy and several laboratory investigations. Erythromycin was administered and the lesion resolved completely within the next 6 weeks. Author comment: ‘We report herein what we believe to be the first case of bacillary angiomatosis in childhood and the first fully documented case occurring during chemotherapy for malignancy.’ Myers SA, et al. Bacillary angiomatosis in a child undergoing chemotherapy. Journal of Pediatrics 121: 574-578, Oct 1992 - USA 800166151 1 Reactions 5 Dec 1992 No. 430 0114-9954/10/0430-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
Transcript of Antineoplastics
Reactions 430 - 5 Dec 1992
Antineoplastics
Bacillary angiomatosis in a child: case reportAn erythematous nodule appeared above the left eyebrow of
a 12-year-old boy 11 months after he was diagnosed withleukaemia. The patient had received prednisone, vincristine,asparaginase, mercaptopurine, methotrexate, cytarabine andhydrocortisone as remission induction and maintenancetherapy. Consolidation therapy consisted of 6 courses ofmethotrexate and asparaginase. Antibiotic therapy reduced thesize of the nodule but the lesion persisted. A diagnosis ofbacillary angiomatosis was confirmed by results of a biopsyand several laboratory investigations. Erythromycin wasadministered and the lesion resolved completely within thenext 6 weeks.
Author comment: ‘We report herein what we believe to bethe first case of bacillary angiomatosis in childhood and thefirst fully documented case occurring during chemotherapy formalignancy.’Myers SA, et al. Bacillary angiomatosis in a child undergoing chemotherapy.Journal of Pediatrics 121: 574-578, Oct 1992 - USA 800166151
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Reactions 5 Dec 1992 No. 4300114-9954/10/0430-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
