Antineoplastics

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Reactions 1389 - 18 Feb 2012 S Antineoplastics Renal failure, toxic shock and severe anaemia leading to death: 3 case reports A 56-year-old man with AIDS developed renal failure, and two 48-year-old men with AIDS developed septic shock or severe anaemia, respectively, during CHOP chemotherapy with cyclophosphamide, doxorubicin, vincristine and prednisone for malignant lymphoma [dosages, routes and duration of treatments to reaction onsets not stated]. All three patients subsequently died from these complications, with survival times ranging from 2 months to less than 1 year. These patients were retrospectively identified. Author comment: In this data, three patients died from the complications of chemotherapy. Gao G, et al. Clinical analysis of 10 AIDS patients with malignant lymphoma. Chinese Journal of Clinical Oncology 38: 1114-1117, No. 18, 30 Sep 2011. Available from: URL: http://dx.doi.org/10.3969/j.issn.1000-8179.2011.18.015 [Chinese; summarised from a translation] - China 803066922 1 Reactions 18 Feb 2012 No. 1389 0114-9954/10/1389-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved

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Page 1: Antineoplastics

Reactions 1389 - 18 Feb 2012

SAntineoplastics

Renal failure, toxic shock and severe anaemialeading to death: 3 case reports

A 56-year-old man with AIDS developed renal failure,and two 48-year-old men with AIDS developed septicshock or severe anaemia, respectively, during CHOPchemotherapy with cyclophosphamide, doxorubicin,vincristine and prednisone for malignant lymphoma[dosages, routes and duration of treatments to reactiononsets not stated]. All three patients subsequently diedfrom these complications, with survival times ranging from2 months to less than 1 year. These patients wereretrospectively identified.

Author comment: In this data, three patients died fromthe complications of chemotherapy.Gao G, et al. Clinical analysis of 10 AIDS patients with malignant lymphoma.Chinese Journal of Clinical Oncology 38: 1114-1117, No. 18, 30 Sep 2011.Available from: URL: http://dx.doi.org/10.3969/j.issn.1000-8179.2011.18.015[Chinese; summarised from a translation] - China 803066922

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Reactions 18 Feb 2012 No. 13890114-9954/10/1389-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved