Antineoplastics

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Reactions 1339 - 19 Feb 2011 S Antineoplastics Small intestinal stricture in an elderly patient: case report A 78-year-old woman with diffuse large B cell lymphoma developed abdominal pain and vomiting after her second cycle of chemotherapy with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone [dosages and routes not stated]. Investigation revealed dilation of the small intestine, and severe stenosis of the ileum approximately 50cm proximal to the ileocaecal valve. Endoscopic dilation therapy with a single-balloon endoscopy was performed. Fluoroscopy demonstrated successful dilation and after 3 days, chemotherapy was reinitiated. She remained free of symptoms after 8 months, and received six cycles of chemotherapy with complete disease remission. Honzawa Y, et al. Successful endoscopic dilation treatment of small intestinal stricture occurring during chemotherapy for malignant lymphoma. Case Reports in Gastroenterology 4: 323-329, No. 3, Sep-Dec 2010. Available from: URL: http:// dx.doi.org/10.1159/000320538 - Japan 803049521 1 Reactions 19 Feb 2011 No. 1339 0114-9954/10/1339-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved

Transcript of Antineoplastics

Page 1: Antineoplastics

Reactions 1339 - 19 Feb 2011

SAntineoplastics

Small intestinal stricture in an elderly patient:case report

A 78-year-old woman with diffuse large B cell lymphomadeveloped abdominal pain and vomiting after hersecond cycle of chemotherapy with rituximab,cyclophosphamide, doxorubicin, vincristine andprednisolone [dosages and routes not stated]. Investigationrevealed dilation of the small intestine, and severe stenosisof the ileum approximately 50cm proximal to the ileocaecalvalve.

Endoscopic dilation therapy with a single-balloonendoscopy was performed. Fluoroscopy demonstratedsuccessful dilation and after 3 days, chemotherapy wasreinitiated. She remained free of symptoms after 8 months,and received six cycles of chemotherapy with completedisease remission.Honzawa Y, et al. Successful endoscopic dilation treatment of small intestinalstricture occurring during chemotherapy for malignant lymphoma. Case Reports inGastroenterology 4: 323-329, No. 3, Sep-Dec 2010. Available from: URL: http://dx.doi.org/10.1159/000320538 - Japan 803049521

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Reactions 19 Feb 2011 No. 13390114-9954/10/1339-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved