Reactions 430 - 5 Dec 1992

Antineoplastics

Bacillary angiomatosis in a child: case reportAn erythematous nodule appeared above the left eyebrow of

a 12-year-old boy 11 months after he was diagnosed withleukaemia. The patient had received prednisone, vincristine,asparaginase, mercaptopurine, methotrexate, cytarabine andhydrocortisone as remission induction and maintenancetherapy. Consolidation therapy consisted of 6 courses ofmethotrexate and asparaginase. Antibiotic therapy reduced thesize of the nodule but the lesion persisted. A diagnosis ofbacillary angiomatosis was confirmed by results of a biopsyand several laboratory investigations. Erythromycin wasadministered and the lesion resolved completely within thenext 6 weeks.

Author comment: ‘We report herein what we believe to bethe first case of bacillary angiomatosis in childhood and thefirst fully documented case occurring during chemotherapy formalignancy.’Myers SA, et al. Bacillary angiomatosis in a child undergoing chemotherapy.Journal of Pediatrics 121: 574-578, Oct 1992 - USA 800166151

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Reactions 5 Dec 1992 No. 4300114-9954/10/0430-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved