Clorazepate
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Reactions 471 - 2 Oct 1993 Clorazepate Adverse effects: clinical study In a multicentre study in the Philippines, 12/562 patients (2%) treated for anxiety disorders with clorazepate (Tranxene®) 5-20 mg/day reported adverse events; these were mild and did not require drug withdrawal. Adverse effects included gastric irritation (n = 6) and drowsiness/sedation (6). There were no reports of withdrawal symptoms. 85% of patients responded to the drug. Author comment: ‘Clorazepate was found to be both a relatively well-tolerated and effective anxiolytic agent.’ Perez GG, et al. A post-marketing surveillance survey on the use of dipotassium clorazepate in clinical practice in the Philippines. Current Medical Research and Opinion 13: 175-181, No. 3, 1993 - Philippines 800219588 1 Reactions 2 Oct 1993 No. 471 0114-9954/10/0471-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
Transcript of Clorazepate
Reactions 471 - 2 Oct 1993
Clorazepate
Adverse effects: clinical studyIn a multicentre study in the Philippines, 12/562 patients
(2%) treated for anxiety disorders with clorazepate(Tranxene®) 5-20 mg/day reported adverse events; these weremild and did not require drug withdrawal.
Adverse effects included gastric irritation (n = 6) anddrowsiness/sedation (6). There were no reports of withdrawalsymptoms. 85% of patients responded to the drug.
Author comment: ‘Clorazepate was found to be both arelatively well-tolerated and effective anxiolytic agent.’Perez GG, et al. A post-marketing surveillance survey on the use of dipotassiumclorazepate in clinical practice in the Philippines. Current Medical Research andOpinion 13: 175-181, No. 3, 1993 - Philippines 800219588
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Reactions 2 Oct 1993 No. 4710114-9954/10/0471-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
