Carbamazepine
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Carbamazepine Erythema multiforme after generic substitution: case report Symptoms of trigeminal neuralgia in a 38-y ear-old woman were well controlled with carbamazepine ('Tegerol'). One week after substitution of a generic formulation , the woman discontinued carbamazepine after developing erythema multiforme. Although skin lesions resolved spontaneousl y, pain associated with trigeminal neuralgia recurred. Following the discovery of the substitution, 'Tegerol ' was re introduced. Pain relief was rapid and skin lesions did not recur. 'Generic formulations may have biologic and therapeutic equivalence, but they are not identical.' Busch RL. Generic carbamazep,ne and erythema multiforme: generic-drug nonequlvatency New Engtand Journal of Medicine 321 692 - 693. 7 Sep 1989 11. Skin eruptions: case report Romaguera C. Grimalt F. Vitaplana J. Azon A. Erythroderma from carbamazeplne. Con tact Dermatitis 20: 304 - 305, Apr 1989 ••
Transcript of Carbamazepine
Carbamazepine Erythema multiforme after generic substitution: case report
Symptoms of trigeminal neuralgia in a 38-year-old woman were well controlled with carbamazepine ('Tegerol') . One week after substitution
of a generic formulation , the woman discontinued carbamazepine after developing erythema multiforme. Although skin lesions resolved spontaneously, pain associated with trigeminal neuralgia recurred. Following the discovery of the substitution, 'Tegerol ' was reintroduced. Pain relief was rapid and skin lesions did not recur.
'Generic formulations may have biologic and therapeutic equivalence, but they are not identical.'
Busch RL. Generic carbamazep,ne and erythema multiforme: generic-drug nonequlvatency New Engtand Journal of Medicine 321 692-693. 7 Sep 1989 11.
Skin eruptions: case report Romaguera C. Grimalt F. Vitaplana J. Azon A. Erythroderma from carbamazeplne. Con tact Dermatitis 20: 304-305, Apr 1989 ••
