Carbamazepine
1
Reactions 1434 - 12 Jan 2013 S Carbamazepine Eyelid myoclonia with absence seizure in a child: case report A 9-year-old girl developed eyelid myoclonia with absence seizure during treatment with carbamazepine. The girl presented with two episodes of seizures which were unprovoked and occurred during sleep. They were characterised by the deviation of her head and eyes to the right and tonic clonic movement of her limbs. She was receiving carbamazepine [route, dosage, duration of treatment to reaction onset, and indication not stated]. Her seizures had started 2 weeks prior to presentation. An EEG revealed generalised discharges. Her carbamazapine was continued. Over the following 2 months, she felt giddy on looking at the sun or the television and her academic performance deteriorated. After 3 months, she had continuous eye blinking for 3 days. EEG revealed absence status. She was diagnosed with eyelid myoclonia with absence seizure. The girl was treated with sodium valproate and benzodiazepines. Her carbamazaepine was withdrawn. Within 48 hours, her seizures stopped. She was discharged receiving clonazepam and sodium valproate. Within the first month of beginning treatment with these two drugs, she had only two brief episodes of eyelid myoclonia. At last follow-up, she had been asymptomatic for the previous 15 months. Author comment: "We report a young girl who presented with [eyelid myoclonia with absence seizure] after introduction of carbamazepine." Azad C, et al. Eyelid myoclonia with absence seizure: Precipitated by carbamazepine therapy. Indian Pediatrics 49: 840-841, No. 10, Oct 2012 - India 803081928 1 Reactions 12 Jan 2013 No. 1434 0114-9954/10/1434-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
Transcript of Carbamazepine
Reactions 1434 - 12 Jan 2013
SCarbamazepine
Eyelid myoclonia with absence seizure in a child:case report
A 9-year-old girl developed eyelid myoclonia with absenceseizure during treatment with carbamazepine.
The girl presented with two episodes of seizures which wereunprovoked and occurred during sleep. They werecharacterised by the deviation of her head and eyes to the rightand tonic clonic movement of her limbs. She was receivingcarbamazepine [route, dosage, duration of treatment toreaction onset, and indication not stated]. Her seizures hadstarted 2 weeks prior to presentation. An EEG revealedgeneralised discharges. Her carbamazapine was continued.Over the following 2 months, she felt giddy on looking at thesun or the television and her academic performancedeteriorated. After 3 months, she had continuous eye blinkingfor 3 days. EEG revealed absence status. She was diagnosedwith eyelid myoclonia with absence seizure.
The girl was treated with sodium valproate andbenzodiazepines. Her carbamazaepine was withdrawn. Within48 hours, her seizures stopped. She was discharged receivingclonazepam and sodium valproate. Within the first month ofbeginning treatment with these two drugs, she had only twobrief episodes of eyelid myoclonia. At last follow-up, she hadbeen asymptomatic for the previous 15 months.
Author comment: "We report a young girl who presentedwith [eyelid myoclonia with absence seizure] afterintroduction of carbamazepine."Azad C, et al. Eyelid myoclonia with absence seizure: Precipitated bycarbamazepine therapy. Indian Pediatrics 49: 840-841, No. 10, Oct 2012 -India 803081928
1
Reactions 12 Jan 2013 No. 14340114-9954/10/1434-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
