Antineoplastics
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Reactions 413 - 8 Aug 1992 ★ Antineoplastics First report of Henoch Schoenlein purpura in an elderly patient: case report 20 days after the second course of antineoplastic therapy comprising cisplatin, ifosfamide and vindesine for primary lung adenocarcinoma, a 76-year-old man was diagnosed with Henoch Schoenlein purpura. Following treatment with prednisolone, the non- thrombocytopenic purpura and the abdominal symptoms disappeared. As the steroid dosage was decreased, proteinuria and haematuria decreased. Purpura and abdominal pains did not recur. Author comment: Henoch Schonlein purpura associated with antineoplastic therapy has not previously been reported. While the relationship with this therapeutic regimen is not proven, the appearance of the symptoms after the second course of treatment would indicate a cause and effect relationship. Murayama J-i, et al. A case of Henoch-Sch¨ onlein purpura that developed after chemotherapy for adenocarcinoma of the lung. Haigan / Japanese Journal of Lung Cancer 32: 259-264, Apr 1992 [Translated from the original published in Japanese] - Japan 800142128 1 Reactions 8 Aug 1992 No. 413 0114-9954/10/0413-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
Transcript of Antineoplastics
Reactions 413 - 8 Aug 1992
★Antineoplastics
First report of Henoch Schoenlein purpura in anelderly patient: case report
20 days after the second course of antineoplastic therapycomprising cisplatin, ifosfamide and vindesine for primarylung adenocarcinoma, a 76-year-old man was diagnosed withHenoch Schoenlein purpura.
Following treatment with prednisolone, the non-thrombocytopenic purpura and the abdominal symptomsdisappeared. As the steroid dosage was decreased, proteinuriaand haematuria decreased. Purpura and abdominal pains didnot recur.
Author comment: Henoch Schonlein purpura associatedwith antineoplastic therapy has not previously been reported.While the relationship with this therapeutic regimen is notproven, the appearance of the symptoms after the secondcourse of treatment would indicate a cause and effectrelationship.Murayama J-i, et al. A case of Henoch-Schonlein purpura that developed afterchemotherapy for adenocarcinoma of the lung. Haigan / Japanese Journal of LungCancer 32: 259-264, Apr 1992 [Translated from the original published in Japanese]- Japan 800142128
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Reactions 8 Aug 1992 No. 4130114-9954/10/0413-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
