Antineoplastics
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Reactions 1357 - 25 Jun 2011 S Antineoplastics Various toxicities and death in an elderly patient: case report A 67-year-old man with diffuse large B-cell lymphoma began receiving rituximab 500mg plus cyclophosphamide 400mg, doxorubicin 40mg, vincristine 2mg and prednisone 60mg [R-CHOP; routes not stated]; the dosages of cyclophosphamide and doxorubicin were increased to 800mg and 60mg, respectively, during cycles 2-4. He developed serious complications following the fourth cycle of R-CHOP, including neutropenia, diarrhoea, intestinal bleeding, peritonitis and pneumonia [duration of treatment to reaction onset not clearly stated]. His condition rapidly deteriorated, and he died from concurrent acute respiratory distress syndrome. Ma Y-J, et al. Primary hepatic diffuse large b cell lymphoma: A case report. Hepatitis Monthly 11: 203-205, No. 3, Mar 2011 - China 803055965 1 Reactions 25 Jun 2011 No. 1357 0114-9954/10/1357-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved
Transcript of Antineoplastics
Reactions 1357 - 25 Jun 2011
SAntineoplastics
Various toxicities and death in an elderly patient:case report
A 67-year-old man with diffuse large B-cell lymphomabegan receiving rituximab 500mg plus cyclophosphamide400mg, doxorubicin 40mg, vincristine 2mg and prednisone60mg [R-CHOP; routes not stated]; the dosages ofcyclophosphamide and doxorubicin were increased to800mg and 60mg, respectively, during cycles 2-4. Hedeveloped serious complications following the fourth cycleof R-CHOP, including neutropenia, diarrhoea, intestinalbleeding, peritonitis and pneumonia [duration of treatmentto reaction onset not clearly stated]. His condition rapidlydeteriorated, and he died from concurrent acute respiratorydistress syndrome.Ma Y-J, et al. Primary hepatic diffuse large b cell lymphoma: A case report.Hepatitis Monthly 11: 203-205, No. 3, Mar 2011 - China 803055965
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Reactions 25 Jun 2011 No. 13570114-9954/10/1357-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved
