Carbamazepine overdose
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Reactions 1340 - 26 Feb 2011 O S Carbamazepine overdose Coma: case report A 15-year-old girl was admitted approximately 4 hours after ingesting an intentional overdose of carbamazepine extended-release 200mg tablets [amount ingested unknown]. The tablets had been prescribed to a family member for epilepsy. Examination revealed loss of consciousness, mydriasis and a Glasgow Coma Scale score of 5. Her BP, RR and oxygen saturation were 110/65mm Hg, 30 breaths/min and 93%, respectively. She was intubated and controlled ventilation was applied. A gastric lavage was performed and activated charcoal was administered. Her plasma carbamazepine level was 54.77 mg/L. Her neurological status subsequently improved. Three days postadmission, her Glasgow Coma Scale score was 11 and she was extubated. She remained in hospital for 6 days, and was subsequently referred to the paediatric psychiatry consultation service. Koraichi AE, et al. Management of carbamazepine overdose in pediatric intensive care unit. Archives de Pediatrie 18: 97-98, No. 1, Jan 2011. Available from: URL: http://dx.doi.org/10.1016/j.arcped.2010.10.023 [French; summarised from a translation] - Morocco 803049654 1 Reactions 26 Feb 2011 No. 1340 0114-9954/10/1340-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved
Transcript of Carbamazepine overdose
Reactions 1340 - 26 Feb 2011
O SCarbamazepine overdose
Coma: case reportA 15-year-old girl was admitted approximately 4 hours
after ingesting an intentional overdose of carbamazepineextended-release 200mg tablets [amount ingestedunknown]. The tablets had been prescribed to a familymember for epilepsy. Examination revealed loss ofconsciousness, mydriasis and a Glasgow Coma Scale scoreof 5. Her BP, RR and oxygen saturation were110/65mm Hg, 30 breaths/min and 93%, respectively. Shewas intubated and controlled ventilation was applied. Agastric lavage was performed and activated charcoal wasadministered. Her plasma carbamazepine level was54.77 mg/L. Her neurological status subsequentlyimproved. Three days postadmission, her Glasgow ComaScale score was 11 and she was extubated. She remained inhospital for 6 days, and was subsequently referred to thepaediatric psychiatry consultation service.Koraichi AE, et al. Management of carbamazepine overdose in pediatric intensivecare unit. Archives de Pediatrie 18: 97-98, No. 1, Jan 2011. Available from: URL:http://dx.doi.org/10.1016/j.arcped.2010.10.023 [French; summarised from atranslation] - Morocco 803049654
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Reactions 26 Feb 2011 No. 13400114-9954/10/1340-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved
