Benazepril
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Reactions 1284 - 16 Jan 2010 S Benazepril Visceral angioedema: case report A 61-year-old man, who had started receiving benazepril 20 mg/day [therapeutic indication not stated] 2 years earlier, presented with a 2-month history of intermittent abdominal pain and meteorism. He subsequently developed vomiting and severe abdominal cramps. Cross sectional imaging revealed jejunal dilation, and diffuse thickening of his small-bowel wall. Over the course of three hospitalisations, he received empirical antibacterials, repeat abdominal imaging, diet modification, esophagogastroduodenoscopy, and multiple biopsies, which showed inflammation. Benazepril-induced visceral angioedema was eventually suspected, and benazepril was empirically withdrawn. Over the next 2 weeks, his symptoms improved steadily. He remained symptom free at last follow-up. Scott D, et al. ANGIOTENSIN-CONVERTING ENZYME (ACE) INHIBITOR- ASSOCIATED ISOLATED VISCERAL ANGIOEDEMA. 2009 Annual Meeting of the American College of Allergy, Asthma and Immunology : abstr. P232, 5 Nov 2009. Available from: URL: http://www.acaai.org - USA 803004476 1 Reactions 16 Jan 2010 No. 1284 0114-9954/10/1284-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved
Transcript of Benazepril
Reactions 1284 - 16 Jan 2010
SBenazepril
Visceral angioedema: case reportA 61-year-old man, who had started receiving benazepril
20 mg/day [therapeutic indication not stated] 2 yearsearlier, presented with a 2-month history of intermittentabdominal pain and meteorism. He subsequentlydeveloped vomiting and severe abdominal cramps. Crosssectional imaging revealed jejunal dilation, and diffusethickening of his small-bowel wall. Over the course of threehospitalisations, he received empirical antibacterials,repeat abdominal imaging, diet modification,esophagogastroduodenoscopy, and multiple biopsies,which showed inflammation. Benazepril-induced visceralangioedema was eventually suspected, and benazepril wasempirically withdrawn. Over the next 2 weeks, hissymptoms improved steadily. He remained symptom freeat last follow-up.Scott D, et al. ANGIOTENSIN-CONVERTING ENZYME (ACE) INHIBITOR-ASSOCIATED ISOLATED VISCERAL ANGIOEDEMA. 2009 Annual Meetingof the American College of Allergy, Asthma and Immunology : abstr. P232, 5 Nov2009. Available from: URL: http://www.acaai.org - USA 803004476
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Reactions 16 Jan 2010 No. 12840114-9954/10/1284-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved
