Antineoplastics
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Reactions 488 - 12 Feb 1994 Antineoplastics Secondary malignancies in patients treated as children and adolescents: incidence study Secondary malignancy occurred in 18/1406 patients treated for cancer with antineoplastic agents and radiation as children or adolescents. The actuarial risk of a second malignant tumour at 25 years after diagnosis was 5.6%. Treatment with doxorubicin or carmustine was associated with a significantly increased risk of secondary malignant tumours. No other treatment variables including surgery, radiotherapy or other chemotherapy were identified as significant risk factors. Green DM, et al. Second malignant tumors following treatment during childhood and adolescence for cancer. Medical and Pediatric Oncology 22: 1-10, No. 1, 1994 - USA 800243250 1 Reactions 12 Feb 1994 No. 488 0114-9954/10/0488-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
Transcript of Antineoplastics
Reactions 488 - 12 Feb 1994
Antineoplastics
Secondary malignancies in patients treated aschildren and adolescents: incidence study
Secondary malignancy occurred in 18/1406 patients treatedfor cancer with antineoplastic agents and radiation as childrenor adolescents. The actuarial risk of a second malignanttumour at 25 years after diagnosis was 5.6%.
Treatment with doxorubicin or carmustine was associatedwith a significantly increased risk of secondary malignanttumours. No other treatment variables including surgery,radiotherapy or other chemotherapy were identified assignificant risk factors.Green DM, et al. Second malignant tumors following treatment during childhoodand adolescence for cancer. Medical and Pediatric Oncology 22: 1-10, No. 1, 1994- USA 800243250
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Reactions 12 Feb 1994 No. 4880114-9954/10/0488-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
