Antineoplastics
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Antineoplastics Benign melanocytic naevi in a child: case report Acute lymphatic l euk aemi a developed in an 8-year-old boy and was treated with antineoplastic therapy. Following a bone marrow transplant from his identical twin, th e patient received cyclophosphamide and mesna therapy with total body irradiation . The patient reco ve red and did not require further treatment. However , he developed a large number of moles , far more than his twin brother. The authors ' . . . could not detect any aetiological factor for the development of the moles other than radiotherapy and chemotherapy, which adds further weight to our hypothesis that immunosuppression stimulates the development of benign melanocytic naevi'. [see Reactions 260: 4, 22 Jut 1989] Hughes B. Bailey CC Excess benign melanocytlc naeVI British Medical Journa l 299 854·855. 30 m Heart disorders: incidence study Wehr M. Gant zer MA Noll B. Krappe J Prospective evaluation of car dlotoxlclty In patients Ireated with differen t comb,nallOns of anllneoplasllc drugs Herz/ Krelslau f 20 411 -416. Oc t 1988 [German] 311 Toxic effects: clinical study MOrlttu L. Earl HM. Souhaml RL. Ash CM. Tobias JS et al Pa tients at risk of chemotherapy· associated toxIcity In small cell lung cancer British Journal o f Cancer 59 801 - 804. May 1989
Transcript of Antineoplastics
Antineoplastics Benign melanocytic naevi in a child: case report
Acute lymphatic leukaemia developed in an 8-year-old boy and was treated with antineoplastic therapy. Following a bone marrow transplant from his identical twin, the patient received cyclophosphamide and mesna therapy with total body irradiation . The patient recovered and did not requ ire further treatment. However, he developed a large number of moles , far more than his twin brother.
The authors ' . . . could not detect any aetiological factor for the development of the moles other than radiotherapy and chemotherapy, which adds further weight to our hypothesis that immunosuppression stimulates the development of benign melanocytic naevi'. [see Reactions 260: 4, 22 Jut 1989] Hughes B. Bailey CC Excess benign melanocytlc naeVI British Medical Journal 299 854·855. 30 ~pl_ m
Heart disorders: incidence study Wehr M. Gantzer MA Noll B. Krappe J Prospective evaluation of cardlotoxlclty In patients Ireated with differen t comb,nallOns of anllneoplasllc drugs Herz/Krelslau f 20 411 -416. Oc t 1988 [German] 311
Toxic effects: clinical study MOrlttu L. Earl HM. Souhaml RL. Ash CM. Tobias JS et al Pa tients at risk of chemotherapy· associated toxIcity In small cell lung cancer British Journal o f Cancer 59 801 -804. May 1989
