Patologi Mata

8/17/2019 Patologi Mata

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PATOLOGI MATA

Fairuz, dr, SpPA


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Anatomi dan Histologi

Kelopak mata (eyelids)

- Cutaneous dan conjunctial

- epitel gepeng !erlapis dan epitel konjuntia yang le!i"

tipis

- kelenjar se!asea (#eis n $ei!om), kelenjar apokrin

($oll) an kelenjar ekrin %ola mata

- ocular glo!e, dan kelenjar air mata

- Konjungtia, kornea, sklera, intraocular

tissue & iris, ciliar !ody, c"oroid, retina, lensa cairanitreous


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KELOPAK MATA (EYELID)


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Chalazion

Se!aceous glands o' eyelid, eit"er

mei!omian glands (deep type) or #eis

glands (super'icial type)

A non-speci'ic response to o!struction o't"ese se!aceous glands Causes

include in'ection and tumor

ipogranulomatous in'lammation *it"lipid drop-out spaces


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Chalazion


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KELENJAR AIR MATA


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+AC.CS/0/0S

Canaculitis

+apat dise!a!kan karena proses in'eksi di

jaringan sekitar seperti konjungtia, "idung Purulen e1udate

Kronis & pene!alan dinding sal acrimal

+AC.0/H0AS0S Karena proses in'lamatory


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+AC.A+230/0S

All ages

acrimal gland

C"ronic in'lammatory cells in'iltration

$ay "ae 'ollicles $ay !e

granulomatous Sometimes may !e

di''icult to distinguis" 'rom lymp"oma


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$0K40C#5S disease

C"ronic dacryoadenitis disertai

pem!esaran kelenjar parotis dan

kelenjar liur lain %enign lymp"oepit"elial lesion

%ila disertai dengan kegagalan sekresi

kelnjar lacrimal dan conjunctial sertakeratokonjungtiitis sicca Sjogren5

syndrome


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Konjungtiva


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Pingueula

+egeneratie process in su!epit"elial

connectie tissue o' !ul!ar conjunctia

Pro!a!ly related to sun e1posure

Focal, yello*is"-gray, raised mass 2lastotic degeneration o' collagen in

su!stantia propria Possi!ly 'oreign !ody giant

cell response (actinic granuloma) Calci'ication

may occur in older lesions C"eck 'or dysplasiaor s6uamous carcinoma in oerlying

epit"elium ule out elasto'i!roma


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Pingueula


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Pte!"giu#

21tend into t"e cornea

$icroscopically usually some actinic

elastosis , aria!le amount o' acute and

c"ronic in'lammation and congestion o'!lood essels

$ore important lesion t"an t"e

pinguecula


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/4$.

Papilloma

S6uamous cell carcinoma

$elanoma maligna


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Ke!atoonu$

Second or t"ird most common indication 'or

keratoplasty

4sually presents during adolescence

Centers o' corneas

2arly, t"inning and asymmetric ectasia o' corneal

stroma .'ten surrounded !y !ro*n ring o' iron deposit

(Fleisc"er7s ring) ater, posterior stromal striae and

possi!ly endot"elial rupture *it" stromal edema and

clouding 2arliest lig"t microscopic c"anges are discontinuities

o' %o*man7s layer, 'illed *it" eit"er epit"elial cells or

'i!ro!lasts 3e1t, stromal t"inning !ecomes o!ious


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Ke!atoonu$


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RETINO%LA&TOMA

$ost common intraocular neoplasm o'

c"ildren

4sually presents !et*een 89 mont"s

and : years Can !e !ilateral

A!out 8;< 'amilial (t"ese "ae

disproportionate s"are o' multi'ocalcases) Autosomal dominant


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S"eets o' neoplastic small round cells *it"

"yperc"romatic nuclei, scant cytoplasm

and many mitoses 4sually e1tensie areas

o' isc"emic necrosis and calci'ication *it"nuclear de!ris, sparing periascular

regions osettes "elp'ul to strengt"en

diagnosis !ut not al*ays seen osettes

occur as t*o types, Flexner-Winterstein*it" small lumen and Homer-Wright

(neuro!lastomatous) *it" central neuropil


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$alignant Poor prognostic 'eatures

include poor di''erentiation ('e*

rosettes), multi'ocality, large size, optic

nere and c"oroidal inasion anditreous seeding


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Retino'la$to#a


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Retinoblastoma

Patologi Mata

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