Antineoplastics

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Page 1: Antineoplastics

Reactions 1304 - 5 Jun 2010

SAntineoplastics

Burkitt’s lymphoma: case reportA woman was diagnosed with breast cancer at the age of

43 years, and underwent left modified radical mastectomyfor stage II intraductal carcinoma. She also receivedsix courses of cyclophosphamide, doxorubicin, thiotepa,methotrexate and fluorouracil [dosages not stated] from1990 to 1991 as adjuvant therapy. Fifteen years later, at theage of 58 years, a pelvic mass was found on routinegynaecologic examination. After a total abdominalhysterectomy with bilateral salpingo-oophorectomy,appendectomy and abdominopelvic lymph nodedissection, she was diagnosed with Burkitt’s lymphoma.Treatment consisted of low-dose vincristine, rituximab,high-dose methotrexate with folinic acid rescue andintrathecal methotrexate. She has remained tumour-freefor 41 months.Hatami M, et al. Primary bilateral ovarian and uterine Burkitt’s lymphomafollowing chemotherapy for breast cancer. Archives of Gynecology and Obstetrics281: 697-702, No. 4, Apr 2010. Available from: URL: http://dx.doi.org/10.1007/s00404-009-1215-9 - USA 803017592

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