Antineoplastics
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Reactions 1516, p29 - 30 Aug 2014 S Antineoplastics Febrile neutropenia: case report An adult patient [age and sex not stated] developed febrile neutropenia following rituximab, cyclophosphamide, doxorubicin, vincristine [routes not stated] and prednisolone (R-CHOP) chemotherapy. The patient, who had a limited-stage diffuse large B-cell lymphoma (DLBCL) and underwent complete tumour resection was enrolled in a study. The patient received 21 day chemotherapy cycles consisting of rituximab 375 mg/m2, cyclophosphamide 750 mg/m2, doxorubicin 50 mg/m2, vincristine [dosage not clearly stated] all on day 1 and oral prednisolone 100 mg/day on days 1–5 for DLBCL treatment. The patient experienced febrile neutropenia after the first R- CHOP cycle [time to reaction onset not clearly stated and outcome not stated]. The patient received minimum 3 cycles of R-CHOP therapy. Author comment: "[1] patient experienced febrile neutropenia after the first cycle of R-CHOP." Jo J, et al. Abbreviated chemotherapy for limited-stage diffuse large B-cell lymphoma after complete resection. Blood Research 49: 115-119, No. 2, Jun 2014. Available from: URL: http://doi.org/10.5045/br.2014.49.2.115 - South Korea 803107478 1 Reactions 30 Aug 2014 No. 1516 0114-9954/14/1516-0001/$14.95 Adis © 2014 Springer International Publishing AG. All rights reserved
Transcript of Antineoplastics
Reactions 1516, p29 - 30 Aug 2014
SAntineoplastics
Febrile neutropenia: case reportAn adult patient [age and sex not stated] developed febrile
neutropenia following rituximab, cyclophosphamide,doxorubicin, vincristine [routes not stated] and prednisolone(R-CHOP) chemotherapy.
The patient, who had a limited-stage diffuse large B-celllymphoma (DLBCL) and underwent complete tumourresection was enrolled in a study. The patient received 21 daychemotherapy cycles consisting of rituximab 375 mg/m2,cyclophosphamide 750 mg/m2, doxorubicin 50 mg/m2,vincristine [dosage not clearly stated] all on day 1 and oralprednisolone 100 mg/day on days 1–5 for DLBCL treatment.The patient experienced febrile neutropenia after the first R-CHOP cycle [time to reaction onset not clearly stated andoutcome not stated]. The patient received minimum 3 cyclesof R-CHOP therapy.
Author comment: "[1] patient experienced febrileneutropenia after the first cycle of R-CHOP."Jo J, et al. Abbreviated chemotherapy for limited-stage diffuse large B-celllymphoma after complete resection. Blood Research 49: 115-119, No. 2, Jun 2014.Available from: URL: http://doi.org/10.5045/br.2014.49.2.115 - SouthKorea 803107478
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Reactions 30 Aug 2014 No. 15160114-9954/14/1516-0001/$14.95 Adis © 2014 Springer International Publishing AG. All rights reserved
