Antineoplastics
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Reactions 1430 - 1 Dec 2012 S Antineoplastics Oral mucositis and anorexia in an elderly patient: case report An 85-year-old man developed oral mucositis and anorexia while receiving cisplatin, gimeracil/oteracil/tegafur [S-1] and docetaxel. The man, who had gastric cancer with pulmonary and lymph node metastases, received two courses of gimeracil/ oteracil/tegafur and cisplatin as fourth-line chemotherapy, followed by three courses of docetaxel as fifth-line treatment [dosages and routes not stated]. The treatment was ineffective, and he developed grade 3 mucositis oral and anorexia [time to reaction onsets not stated]. His canker sores made feeding difficult, and he was hospitalised for further treatment. Chemotherapy was discontinued, and the man received best supportive care. His canker sores resolved, and his quality of life improved. Author comment: "[The patient] suffered grade 3 mucositis oral and anorexia throughout 2 courses of fourth- line S-1 + [cisplatin] therapy and fifth-line docetaxel therapy." Minagawa R, et al. A case of elderly advanced gastric cancer patient with multiple liver metastases effectively treated by hepatic arterial infusion chemotherapy. Gan to Kagaku Ryoho 37: 2484-2486, No. 12, Nov 2010 [Japanese; summarised from a translation] - Japan 803080406 1 Reactions 1 Dec 2012 No. 1430 0114-9954/10/1430-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
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Transcript of Antineoplastics
Reactions 1430 - 1 Dec 2012
SAntineoplastics
Oral mucositis and anorexia in an elderly patient:case report
An 85-year-old man developed oral mucositis andanorexia while receiving cisplatin, gimeracil/oteracil/tegafur[S-1] and docetaxel.
The man, who had gastric cancer with pulmonary andlymph node metastases, received two courses of gimeracil/oteracil/tegafur and cisplatin as fourth-line chemotherapy,followed by three courses of docetaxel as fifth-linetreatment [dosages and routes not stated]. The treatmentwas ineffective, and he developed grade 3 mucositis oraland anorexia [time to reaction onsets not stated]. Hiscanker sores made feeding difficult, and he washospitalised for further treatment.
Chemotherapy was discontinued, and the man receivedbest supportive care. His canker sores resolved, and hisquality of life improved.
Author comment: "[The patient] suffered grade 3mucositis oral and anorexia throughout 2 courses of fourth-line S-1 + [cisplatin] therapy and fifth-line docetaxel therapy."Minagawa R, et al. A case of elderly advanced gastric cancer patient with multipleliver metastases effectively treated by hepatic arterial infusion chemotherapy. Ganto Kagaku Ryoho 37: 2484-2486, No. 12, Nov 2010 [Japanese; summarised from atranslation] - Japan 803080406
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Reactions 1 Dec 2012 No. 14300114-9954/10/1430-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
