Burzynski’s ‘antineoplastons’

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L4 RESEARCH & DEVELOPMENT Burzynski's 'antineoplastons': don't be misled Claims made by Dr Burzynski in support of his theory that there is an antineoplastic biochemical surveillance system in humans cannot be verified, says Dr S Green from New York, USA. Dr Burzynski believes that naturally occurring peptides with antineoplastic activity ('antineoplastons') can be found in urine. He based the rationale of existence of antineoplastons on the following: Cancer can spontaneously regress; therefore, there must be a 'normalising' mechanism Certain information-carrying chemicals can induce cell differentiation Peptides carry information that induce biochemical reactions Not everyone develops cancer despite the production of cancer cells. However, on review of the literature produced by Burzynski, there is no evidence supporting the existence of a naturally occurring antineoplastic surveillance system in humans. Different urinary antineoplastons identified by Dr Burzynski have not been proven to be distinct from each other or to have antineoplastic activity. A-tO, claimed to be the common factor in all urine antineoplaston fractions, is actually insoluble in body fluids; therefore, it cannot be part of the body's anticancer system. Solubilising A-IO converts it to a noninformation carrying peptide. Green S. Antineoplastons. An unproved cancer therapy. Journal of the American Medical Acadamy 267: 2924-2928,3 Jun 1992 "" 13 Jun 1992 INPHARMAII ISSN 0156-2703/92/0613-0014/$1.00/0 @ Adi. Inl ...natiallallJd

Transcript of Burzynski’s ‘antineoplastons’

Page 1: Burzynski’s ‘antineoplastons’

L4 RESEARCH & DEVELOPMENT

Burzynski's 'antineoplastons': don't be misled

Claims made by Dr Burzynski in support of his theory that there is an antineoplastic biochemical surveillance system in humans cannot be verified, says Dr S Green from New York, USA.

Dr Burzynski believes that naturally occurring peptides with antineoplastic activity ('antineoplastons') can be found in urine. He based the rationale of existence of antineoplastons on the following: • Cancer can spontaneously regress; therefore,

there must be a 'normalising' mechanism • Certain information-carrying chemicals can

induce cell differentiation • Peptides carry information that induce

biochemical reactions • Not everyone develops cancer despite the

production of cancer cells. However, on review of the literature produced

by Burzynski, there is no evidence supporting the existence of a naturally occurring antineoplastic surveillance system in humans. Different urinary antineoplastons identified by Dr Burzynski have not been proven to be distinct from each other or to have antineoplastic activity. A-tO, claimed to be the common factor in all urine antineoplaston fractions, is actually insoluble in body fluids; therefore, it cannot be part of the body's anticancer system. Solubilising A-IO converts it to a noninformation carrying peptide. Green S. Antineoplastons. An unproved cancer therapy. Journal of the American Medical Acadamy 267: 2924-2928,3 Jun 1992 ""

13 Jun 1992 INPHARMAII ISSN 0156-2703/92/0613-0014/$1.00/0 @ Adi. Inl ... natiallallJd